Brief Information of the Compound and Protein
Compound Name
(2S)-2-[(4-{2-[(6R)-2-amino-4-oxo-1H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidin-6-yl]ethyl}phenyl)formamido]pentanedioic acid
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PubChem ID
CID: 135413518
SID: 12014547
Canonical SMILES
Nc1nc2NC[C@H](CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)Cc2c(=O)[nH]1
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Compound Formula C21H25N5O6
Compound Structure
Protein Name
Trifunctional purine biosynthetic protein adenosine-3
Protein Classification
Enzyme
>
Ligase
Uniprot ID
P22102
Gene Name
GART
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000423 IGROV-1 Homo sapiens (Human)  1
1
IC50 = 5.77 nM
   TI
   LI
   LO
   TS
CL000220 KB Homo sapiens (Human)  1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 6 nM
2 Ki = 60 nM
3 Ki = 130 nM