Brief Information of the Compound and Protein
Compound Name
3-[[4-[(1S)-1-[5-(6-methoxynaphthalen-2-yl)-3-[2-methyl-5-(trifluoromethyl)phenyl]pyrazol-1-yl]ethyl]benzoyl]amino]propanoic acid
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PubChem ID
CID: 60171062
SID: 144120419
Canonical SMILES
COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(ccc1C)C(F)(F)F
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Compound Formula C34H30F3N3O4
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 9.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 27.4 nM
   TI
   LI
   LO
   TS