Brief Information of the Compound and Protein
Compound Name
4-chloro-N-[4-fluoro-3-[(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)carbamoyl]phenyl]-3-(trifluoromethyl)benzamide
    Show/Hide
PubChem ID
CID: 71456644
SID: 163436161
Canonical SMILES
COc1n[nH]c2ncc(NC(=O)c3cc(NC(=O)c4ccc(Cl)c(c4)C(F)(F)F)ccc3F)cc12
    Show/Hide
Compound Formula C22H14ClF4N5O3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000212 Malme-3M Homo sapiens (Human)  1
1
IC50 = 96 nM
   TI
   LI
   LO
   TS