Brief Information of the Compound and Protein
Compound Name
2-chloro-5-[[3-(2-cyanopropan-2-yl)benzoyl]amino]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
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PubChem ID
CID: 71456645
SID: 163436162
Canonical SMILES
COc1n[nH]c2ncc(NC(=O)c3cc(NC(=O)c4cccc(c4)C(C)(C)C#N)ccc3Cl)cc12
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Compound Formula C25H21ClN6O3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000212 Malme-3M Homo sapiens (Human)  1
1
IC50 = 22 nM
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