Brief Information of the Compound and Protein
Compound Name
3-(2-cyanopropan-2-yl)-N-[3-[(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)carbamoyl]phenyl]benzamide
    Show/Hide
PubChem ID
CID: 71460336
SID: 163436007
Canonical SMILES
COc1n[nH]c2ncc(NC(=O)c3cccc(NC(=O)c4cccc(c4)C(C)(C)C#N)c3)cc12
    Show/Hide
Compound Formula C25H22N6O3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000212 Malme-3M Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS