Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-fluoro-3-(2-fluoro-4-iodoanilino)-N-[(2S)-2-hydroxypropoxy]furo[3,2-c]pyridine-2-carboxamide
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 PubChem ID
CID: 46926364
SID: 136913766
Canonical SMILES
C[C@H](O)CONC(=O)c1oc2c(F)cncc2c1Nc1ccc(I)cc1F
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Compound Formula C17H14F2IN3O4
Compound Structure
Protein Name
 Protein Info 
Dual specificity mitogen-activated protein kinase kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE7 family
Uniprot ID
Q02750
Gene Name
MAP2K1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 7.2 nM
   TI
   LI
   LO
   TS
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 35 nM