Brief Information of the Compound and Protein
Compound Name
3-(3-carboxyphenyl)-5,6-dihydroxy-1H-indole-2-carboxylic acid
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PubChem ID
CID: 70689184
SID: 163505796
Canonical SMILES
OC(=O)c1[nH]c2cc(O)c(O)cc2c1-c1cccc(c1)C(O)=O
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Compound Formula C16H11NO6
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
EC50 = 24900 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 75700 nM
   TI
   LI
   LO
   TS