Brief Information of the Compound and Protein
Compound Name
5-bromo-4-N-(5-methyl-1H-pyrazol-3-yl)-2-N-(2-pyridin-3-ylethyl)pyrimidine-2,4-diamine
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PubChem ID
CID: 56973548
SID: 144085206
Canonical SMILES
Cc1cc(Nc2nc(NCCc3cccnc3)ncc2Br)[nH]n1
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Compound Formula C15H16BrN7
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 2511.89 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 501.19 nM
   TI
   LI
   LO
   TS