Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(1-methylbenzimidazol-2-yl)methyl]-4-morpholin-4-yl-1H-pyrimidin-6-one
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 PubChem ID
CID: 135566644
SID: 104226644
Canonical SMILES
Cn1c(Cc2nc(cc(=O)[nH]2)N2CCOCC2)nc2ccccc12
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Compound Formula C17H19N5O2
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000144 3T3 MEFs WT
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 86 nM
   TI
   LI
   LO
   TS
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
2
IC50 = 188 nM
   TI
   LI
   LO
   TS
CL000146 S21
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 99 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 99 nM
   TI
   LI
   LO
   TS