Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-(1-anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
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 PubChem ID
CID: 9907093
SID: 14877022
Canonical SMILES
CC(Nc1ccccc1)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1
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Compound Formula C21H24N4O2
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000144 3T3 MEFs WT
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CL000196 MDA-MB-468
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS
CL000146 S21
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
2
IC50 = 52 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 49 nM
2 IC50 = 65 nM
3 IC50 = 2000 nM