Brief Information of the Compound and Protein
Compound Name
4-Amino-thieno[3,2-d]pyrimidine-7-carboxylic Acid [2,6-Difluoro-3-(propane-1-sulfonylamino)-phenyl]-amide
    Show/Hide
PubChem ID
CID: 50995710
SID: 117641880
Canonical SMILES
CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2csc3c(N)ncnc23)c1F
    Show/Hide
Compound Formula C16H15F2N5O3S2
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000212 Malme-3M Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS