Brief Information of the Compound and Protein
Compound Name
N-(2,4-Difluoro-3-(3-(6-(methylamino)pyrimidin-4-yl)-ureido)phenyl)propane-1-sulfonamide
    Show/Hide
PubChem ID
CID: 50997340
SID: 117643529
Canonical SMILES
CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)Nc2cc(NC)ncn2)c1F
    Show/Hide
Compound Formula C15H18F2N6O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000212 Malme-3M Homo sapiens (Human)  1
1
IC50 = 168 nM
   TI
   LI
   LO
   TS