Brief Information of the Compound and Protein
Compound Name
benzo[7]annulene-8-carboxylic acid, 5
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PubChem ID
CID: 5098885
SID: 123051503
Canonical SMILES
OC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1
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Compound Formula C12H8O6
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  2
1
EC50 = 54 nM
   TI
   LI
   LO
   TS
2
IC50 = 110 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 12400 nM
   TI
   LI
   LO
   TS