Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(2-anilinoquinazolin-6-yl)oxy-N-methylpyridine-2-carboxamide
    Show/Hide
 PubChem ID
CID: 57399505
Canonical SMILES
CNC(=O)c1cc(Oc2ccc3nc(Nc4ccccc4)ncc3c2)ccn1
    Show/Hide
Compound Formula C21H17N5O2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CL000313 SK-MEL-28
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS