Brief Information of the Compound and Protein
Compound Name
[(3aR,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
    Show/Hide
PubChem ID
CID: 57393651
Canonical SMILES
CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1cc2cccnc2[nH]1
    Show/Hide
Compound Formula C15H18N4O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 973 nM
   TI
   LI
   LO
   TS