Brief Information of the Compound and Protein
Compound Name
(4-methylpiperazin-1-yl)-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
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PubChem ID
CID: 57392460
SID: 152229917
Canonical SMILES
CN1CCN(CC1)C(=O)c1cc2cccnc2[nH]1
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Compound Formula C13H16N4O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3100 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
2
Ki > 29900 nM
   TI
   LI
   LO
   TS