Brief Information of the Compound and Protein
Compound Name
 Compound Info 
12-epi-Salvinorin A
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 PubChem ID
CID: 25242485
SID: 57644910
Canonical SMILES
COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@H](C[C@]21C)c1ccoc1
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Compound Formula C23H28O8
Compound Structure
Protein Name
 Protein Info 
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
EC50 = 41 nM
   TI
   LI
   LO
   TS
2
EC50 = 84 nM
   TI
   LI
   LO
   TS
3
EC50 = 720 nM
   TI
   LI
   LO
   TS
4
Ki = 17 nM
   TI
   LI
   LO
   TS
5
Ki = 41 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 382 nM
   TI
   LI
   LO
   TS