Brief Information of the Compound and Protein
Compound Name
3-amino-6-chloro-5-[(3S)-3-ethyl-4-[1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]piperazin-1-yl]pyrazine-2-carboxamide
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PubChem ID
CID: 57392573
Canonical SMILES
CC[C@H]1CN(CCN1C1CCN(Cc2ccc(OC(F)(F)F)cc2)CC1)c1nc(N)c(nc1Cl)C(N)=O
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Compound Formula C24H31ClF3N7O2
Compound Structure
Protein Name
C-X-C chemokine receptor type 3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P49682
Gene Name
CXCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 3.7 nM
   TI
   LI
   LO
   TS