Brief Information of the Compound and Protein
Compound Name
N-[2-chloro-5-(3-morpholin-4-ylquinoxalin-6-yl)pyridin-3-yl]-4-fluorobenzenesulfonamide
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PubChem ID
CID: 44609387
SID: 87459250
Canonical SMILES
Fc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncc(nc2c1)N1CCOCC1
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Compound Formula C23H19ClFN5O3S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 3.1 nM
   TI
   LI
   LO
   TS
2
Ki = 0.8 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS