Brief Information of the Compound and Protein
Compound Name
N-benzyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine
    Show/Hide
PubChem ID
CID: 46228071
Canonical SMILES
CN1CCN(CC1)c1cc(NCc2ccccc2)ncn1
    Show/Hide
Compound Formula C16H21N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 207 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 417 nM
   TI
   LI
   LO
   TS