Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[(3S)-3-[[6-(3,3-dimethylbutylamino)pyrimidin-4-yl]amino]pyrrolidin-1-yl]methyl]-6-fluorophenol
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 PubChem ID
CID: 57391122
Canonical SMILES
CC(C)(C)CCNc1cc(N[C@H]2CCN(Cc3cccc(F)c3O)C2)ncn1
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Compound Formula C21H30FN5O
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 20000 nM
   TI
   LI
   LO
   TS