Brief Information of the Compound and Protein
Compound Name
2-(3-cyano-4-methyl-1-oxaspiro[4.5]dec-3-en-2-ylidene)propanedinitrile
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PubChem ID
CID: 21337669
SID: 124399481
Canonical SMILES
CC1=C(C#N)C(OC11CCCCC1)=C(C#N)C#N
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Compound Formula C14H13N3O
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  2
1
EC50 = 45900 nM
   TI
   LI
   LO
   TS
2
IC50 = 16400 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS