Brief Information of the Compound and Protein
Compound Name
2-[3-cyano-4-methyl-5-phenyl-5-(trifluoromethyl)furan-2-ylidene]propanedinitrile
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PubChem ID
CID: 11674067
SID: 16778046
Canonical SMILES
CC1=C(C#N)C(OC1(c1ccccc1)C(F)(F)F)=C(C#N)C#N
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Compound Formula C16H8F3N3O
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  2
1
EC50 = 3500 nM
   TI
   LI
   LO
   TS
2
IC50 = 1940 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS