Brief Information of the Compound and Protein
Compound Name
(1S,2S,6R,14R,15R,16R)-16-[(2R)-1-(2-bicyclo[2.2.1]heptanyl)-2-hydroxypropan-2-yl]-5-(cyclopropylmethyl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
    Show/Hide
PubChem ID
CID: 56658044
Canonical SMILES
CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)CC1CC4CCC1C4)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45
    Show/Hide
Compound Formula C33H45NO4
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 111 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS