Brief Information of the Compound and Protein
Compound Name
2-hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethynyl]benzoic acid
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PubChem ID
CID: 19423428
SID: 134216634
Canonical SMILES
OC(=O)c1cc(ccc1O)C#Cc1ccc(cc1)S(=O)(=O)Nc1ccccn1
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Compound Formula C20H14N2O5S
Compound Structure
Protein Name
Cystine/glutamate transporter
Protein Classification
Transporter
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Electrochemical transporter
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SLC superfamily of solute carriers
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SLC03 and SLC07 families of heteromeric amino acid transporters (HATs)
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SLC07 Cationic amino acid transporter/glycoprotein-associated family
Uniprot ID
Q9UPY5
Gene Name
SLC7A11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 70000 nM