Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1aS,7E,7aS)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide
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 PubChem ID
CID: 44572113
Canonical SMILES
O\N=C1/[C@@H]2C[C@@]2(Oc2ccccc12)C(=O)Nc1ccccc1
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Compound Formula C17H14N2O3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 4
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14833
Gene Name
GRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
EC50 = 3100 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 4740 nM
   TI
   LI
   LO
   TS
2
EC50 > 5000 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 2250 nM
   TI
   LI
   LO
   TS
2
EC50 = 2500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1400 nM