Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(2S,4R)-4-tert-butylsulfanyl-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
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 PubChem ID
CID: 56678649
Canonical SMILES
Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4C[C@@H](C[C@H]4CO)SC(C)(C)C)cc3)nn3cccc23)n[nH]1
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Compound Formula C27H34N8O2S2
Compound Structure
Protein Name
 Protein Info 
Aurora kinase B
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
Q96GD4
Gene Name
AURKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1790 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 39 nM