Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(1R,2S,5S)-2-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
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 PubChem ID
CID: 56668419
Canonical SMILES
Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4C[C@H]5C[C@H]5[C@H]4CO)cc3)nn3cccc23)n[nH]1
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Compound Formula C24H26N8O2S
Compound Structure
Protein Name
 Protein Info 
Aurora kinase B
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
Q96GD4
Gene Name
AURKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 179 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 15 nM