Brief Information of the Compound and Protein
Compound Name
1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6,7- dimethoxy- quinalozin- 4-yloxy)phenyl) urea
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PubChem ID
CID: 56668698
Canonical SMILES
COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(on4)C(C)(C)C)ccc3F)c2cc1OC
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Compound Formula C24H24FN5O5
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 62 nM
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