Brief Information of the Compound and Protein
Compound Name
1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- 6-(2- morpholino- ethoxy) quinazolin-4- yloxy)phenyl) urea
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PubChem ID
CID: 44243219
SID: 85263655
Canonical SMILES
COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCOCC1
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Compound Formula C29H34N6O6
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 52 nM
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