Brief Information of the Compound and Protein
Compound Name
1-(4-chloro-3- (trifluoromethyl) phenyl)- 3-(3-(6,7- dimethoxy- quinazolin- 4- yloxy)phenyl) urea
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PubChem ID
CID: 56665517
Canonical SMILES
COc1cc2ncnc(Oc3cccc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)c3)c2cc1OC
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Compound Formula C24H18ClF3N4O4
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 696 nM
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