Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
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 PubChem ID
CID: 60795
SID: 15103350
Canonical SMILES
Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
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Compound Formula C23H27Cl2N3O2
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
Ki = 57.54 nM
   TI
   LI
   LO
   TS
2
Ki = 63 nM
   TI
   LI
   LO
   TS
3
Ki = 81 nM
   TI
   LI
   LO
   TS
4
Ki = 100 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 57.1 nM
   TI
   LI
   LO
   TS
2
Ki = 168 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 251 nM
2 Ki = 510 nM
3 Ki = 1000 nM