Brief Information of the Compound and Protein
Compound Name
2,6-difluoro-N-(3-(2-isopropyl-5-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ylamino)pyrimidin-4-yl)thiazol-4-yl)phenyl)benzamide
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PubChem ID
CID: 56663303
Canonical SMILES
CC(C)c1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Nc3ccc4c(c3)CN(C)CC4)n2)s1
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Compound Formula C33H30F2N6OS
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000313 SK-MEL-28 Homo sapiens (Human)  1
1
EC50 = 580 nM
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