Brief Information of the Compound and Protein
Compound Name
N-[4-(3-bromoanilino)-3-cyanoquinolin-6-yl]prop-2-enamide
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PubChem ID
CID: 9930439
SID: 14903163
Canonical SMILES
Brc1cccc(Nc2c(cnc3ccc(NC(=O)C=C)cc23)C#N)c1
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Compound Formula C19H13BrN4O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000254 DiFi Homo sapiens (Human)  1
1
IC50 = 588.84 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.7 nM
2 IC50 = 86.9 nM
3 IC50 = 590 nM