Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-amino-6-(4-((4-hydroxybutan-2-yl)sulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide
    Show/Hide
 PubChem ID
CID: 52937660
SID: 123077705
Canonical SMILES
CC(CCO)S(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)C(=O)Nc1ccccc1
    Show/Hide
Compound Formula C21H22N4O4S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase ATR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13535
Gene Name
ATR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 380 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM