Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5S)-N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
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 PubChem ID
CID: 11615489
SID: 16718337
Canonical SMILES
CCCN(CCC)[C@H]1CCn2nccc2C1
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Compound Formula C13H23N3
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
Ki = 4 nM
   TI
   LI
   LO
   TS
2
Ki = 14 nM
   TI
   LI
   LO
   TS
3
Ki = 31 nM
   TI
   LI
   LO
   TS
4
Ki = 110 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
Ki = 45 nM
   TI
   LI
   LO
   TS
2
Ki = 150 nM
   TI
   LI
   LO
   TS
3
Ki = 420 nM
   TI
   LI
   LO
   TS
4
Ki = 840 nM
   TI
   LI
   LO
   TS
5
Ki = 8100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 3.4 nM
2 Ki = 8.4 nM