Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-chloro-2-propyl-6-[4-[[6-(trifluoromethyl)pyridin-3-yl]methoxy]phenyl]isoquinolin-1-one
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 PubChem ID
CID: 46917791
SID: 99383109
Canonical SMILES
CCCn1ccc2cc(cc(Cl)c2c1=O)-c1ccc(OCc2ccc(nc2)C(F)(F)F)cc1
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Compound Formula C25H20ClF3N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 251.19 nM
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