Brief Information of the Compound and Protein
Compound Name
1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea
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PubChem ID
CID: 44464338
SID: 85743745
Canonical SMILES
FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)c2cccnc2)cc1
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Compound Formula C19H19F3N4O3
Compound Structure
Protein Name
Bifunctional epoxide hydrolase 2
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S33 family
Uniprot ID
P34913
Gene Name
EPHX2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 6.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.6 nM