Brief Information of the Compound and Protein
Compound Name
1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
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PubChem ID
CID: 24899523
SID: 53783906
Canonical SMILES
CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F
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Compound Formula C14H18F3N3O3S
Compound Structure
Protein Name
Bifunctional epoxide hydrolase 2
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S33 family
Uniprot ID
P34913
Gene Name
EPHX2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.7 nM
2 Ki = 7.16 nM