Brief Information of the Compound and Protein
Compound Name
1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazin-1-yl)-1H-indole
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PubChem ID
CID: 23653135
SID: 46525068
Canonical SMILES
CC(C)c1ccc(cc1)S(=O)(=O)n1cc(N2CCN(C)CC2)c2ccccc12
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Compound Formula C22H27N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
Ki = 3.4 nM
   TI
   LI
   LO
   TS