Brief Information of the Compound and Protein
Compound Name
3-(4-((3-(3,5-dichlorophenyl)-5-(4-(trifluoromethoxy)phenyl)-1H-pyrazol-1-yl)methyl)benzamido)propanoic acid
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PubChem ID
CID: 9985625
SID: 14963646
Canonical SMILES
OC(=O)CCNC(=O)c1ccc(Cn2nc(cc2-c2ccc(OC(F)(F)F)cc2)-c2cc(Cl)cc(Cl)c2)cc1
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Compound Formula C27H20Cl2F3N3O4
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  4
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
2
IC50 = 84 nM
   TI
   LI
   LO
   TS
3
IC50 = 86.2 nM
   TI
   LI
   LO
   TS
4
IC50 = 113.8 nM
   TI
   LI
   LO
   TS