Brief Information of the Compound and Protein
Compound Name
4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine
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PubChem ID
CID: 49765254
SID: 103021557
Canonical SMILES
CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(cn2)N2CCC(CC2)N(C)C)n1
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Compound Formula C22H29ClN8
Compound Structure
Protein Name
Cyclin-dependent kinase 4
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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CMGC protein kinase group
Uniprot ID
P11802
Gene Name
CDK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000182 JeKo-1 Homo sapiens (Human)  2
1
IC50 = 324 nM
   TI
   LI
   LO
   TS
2
IC50 = 365 nM
   TI
   LI
   LO
   TS