Brief Information of the Compound and Protein
Compound Name
1-(biphenyl-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione
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PubChem ID
CID: 45281794
SID: 96044693
Canonical SMILES
FC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccccc3)C(=O)C(=O)c2c1
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Compound Formula C22H14F3NO3
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P08912
Gene Name
CHRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1600 nM
   TI
   LI
   LO
   TS
2
EC50 = 2700 nM
   TI
   LI
   LO
   TS