Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propoxy)phenyl)urea
    Show/Hide
 PubChem ID
CID: 52943968
Canonical SMILES
NC(=O)Nc1cccc(OCC(O)CNC2CCN(CC2)c2ncnc3scc(-c4ccccc4)c23)c1
    Show/Hide
Compound Formula C27H30N6O3S
Compound Structure
Protein Name
 Protein Info 
Beta-2 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P07550
Gene Name
ADRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1280 nM
   TI
   LI
   LO
   TS
2
Ki = 139 nM
   TI
   LI
   LO
   TS