Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
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 PubChem ID
CID: 176870
SID: 14878691
Canonical SMILES
COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC
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Compound Formula C22H23N3O4
Compound Structure
Protein Name
 Protein Info 
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 83100 nM
   TI
   LI
   LO
   TS
CL000117 SF539
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 83100 nM
   TI
   LI
   LO
   TS
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 12.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2300 nM
2 Kd = 1400 nM