Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3Z)-3-{[4-(dimethylamino)phenyl]methylidene}-2,3-dihydro-1H-indol-2-one
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 PubChem ID
CID: 6450842
SID: 14750294
Canonical SMILES
CN(C)c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1
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Compound Formula C17H16N2O
Compound Structure
Protein Name
 Protein Info 
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3750 nM
   TI
   LI
   LO
   TS
CL000117 SF539
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
2
IC50 = 3750 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19400 nM