Brief Information of the Compound and Protein
Compound Name
(3R,6R,7S,8E,10S,11S,12E,14E,16S,18R,19R,20R,21S)-3,6,21-trihydroxy-6,10,12,16,20-pentamethyl-7-{N-[(5S)-6-{N-methyl-N-[2-(N-methyl-N-{5-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)ethyl]amino}-6-oxo-5-(N-{4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzoyl}amino)hexyl]carbamoyloxy}-18,19-epoxytricosa-8,12,14-triene-11-olide
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PubChem ID
CID: 52941963
Canonical SMILES
CC[C@H](O)[C@@H](C)[C@H]1O[C@@H]1C[C@H](C)/C=C/C=C(\C)[C@H]1OC(=O)C[C@H](O)CC[C@@](C)(O)[C@@H](OC(=O)NCCCC[C@H](NC(=O)c2ccc(C3(C(F)(F)F)N=N3)cc2)C(=O)N(C)CCN(C)C(=O)CCCC[C@H]2SC[C@H]3NC(=O)N[C@H]32)CC[C@@H]1C
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Compound Formula C58H87F3N8O12S
Compound Structure
Protein Name
Splicing factor 3B subunit 3
Protein Classification
Other nuclear protein
Uniprot ID
Q15393
Gene Name
SF3B3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  1
1
IC50 = 644.8 nM
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