Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[1]pyrindin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid
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 PubChem ID
CID: 44360674
Canonical SMILES
CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1
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Compound Formula C36H43NO3S
Compound Structure
Protein Name
 Protein Info 
Cysteinyl leukotriene receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Leukotriene receptor
Uniprot ID
Q9Y271
Gene Name
CYSLTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 0.34 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.56 nM
   TI
   LI
   LO
   TS