Brief Information of the Compound and Protein
Compound Name
(3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridin-2-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
    Show/Hide
PubChem ID
CID: 1509257
Canonical SMILES
CCN1CCc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2C1
    Show/Hide
Compound Formula C22H24N4OS
Compound Structure
Protein Name
Isocitrate dehydrogenase [NADP] cytoplasmic
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
O75874
Gene Name
IDH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 14581 nM
   TI
   LI
   LO
   TS