Brief Information of the Compound and Protein
Compound Name
1-(3-chloro-5-(5-chloro-4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-ylcarbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid
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PubChem ID
CID: 49798018
Canonical SMILES
OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(c(Cl)s1)-c1ccc(F)c(c1)C(F)(F)F
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Compound Formula C22H16Cl2F4N4O3S
Compound Structure
Protein Name
Thrombopoietin receptor
Protein Classification
Membrane receptor
Uniprot ID
P40238
Gene Name
MPL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
EC50 = 86 nM
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